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1

Synthesis and SAR of highly potent and selective dopamine D3-receptor antagonists: Quinolin(di)one and benzazepin(di)one derivatives

Hervé Geneste, Gisela Backfisch, Wilfried Braje, Jürgen Delzer, Andreas Haupt, Charles W. Hutchins, Linda L. King, Wilfried Lubisch, Gerd Steiner, Hans-Jürgen Teschendorf, Liliane Unger, Wolfgang Wern

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 267 KB

english, 2006

2

Fuel savings through steering and braking technologies

Dipl.-Ing. Frank Lubischer,Dipl.-Ing. Josef Pickenhahn…

Journal:

ATZ worldwide eMagazine

Year:

2008

Language:

english

File:

PDF, 1.35 MB

english, 2008

3

Stock Healthy, Shop Healthy: If Customers Demand It, Healthy Options Will Come

Lubischer, Kara, Keller, Kimberly

Journal:

Journal of Nutrition Education and Behavior

Year:

2017

Language:

english

File:

PDF, 55 KB

english, 2017

4

Target muscles and sensory afferents do not influence steroid-regulated, segment-specific death of identified motoneurons in Manduca sexta

Jane L. Lubischer, Janis C. Weeks

Journal:

Developmental Neurobiology

Year:

1996

Language:

english

File:

PDF, 1.13 MB

english, 1996

5

Mehrstufenreaktionen unter Beteiligung latenter α-hetero-substituierter Carbanionen. Zur Umsetzung von 2-Pyrrolcarbaldehyd mit 1,2-disubstituierten Ethenen

Wilhelm Flitsch, Wilfried Lubisch

Journal:

European Journal of Inorganic Chemistry

Year:

1982

Language:

german

File:

PDF, 480 KB

german, 1982

6

Zur Umsetzung von 2-Pyrrolcarbaldehyd mit heterosubstituierten Ethenen

Wilhelm Flitsch, Wilfried Lubisch

Journal:

European Journal of Inorganic Chemistry

Year:

1984

File:

PDF, 638 KB

1984

7

ChemInform Abstract: Pyrrolylquinoxalinediones: A New Class of AMPA Receptor Antagonists.

W. LUBISCH, B. BEHL, H. P. HOFMANN

Journal:

Year:

1997

File:

PDF, 29 KB

1997

8

ChemInform Abstract: Pyrrolylquinoxalinediones: The Importance of Pyrrolic Substitution on AMPA Receptor Binding.

W. LUBISCH, B. BEHL, H. P. HOFMANN

Journal:

Year:

1997

File:

PDF, 27 KB

1997

9

ChemInform Abstract: Pyrrolylquinoxalinediones: Dicarboxylates as Highly Potent AMPA Receptor Antagonists.

W. LUBISCH, B. BEHL, H. P. HOFMANN, H. J. TESCHENDORF

Journal:

Year:

1998

File:

PDF, 28 KB

1998

10

ChemInform Abstract: Synthesis and Biological Evaluation of Novel Piperidine Carboxamide Derived Calpain Inhibitors.

W. Lubisch, H. P. Hofmann, H. J. Treiber, A. Moeller

Journal:

Year:

2000

File:

PDF, 28 KB

2000

11

ChemInform Abstract: Discovery of Phenyl Alanine Derived Ketoamides Carrying Benzoyl Residues as Novel Calpain Inhibitors.

W. Lubisch, A. Moeller

Journal:

Year:

2002

File:

PDF, 29 KB

2002

12

ChemInform Abstract: Pyrrolylquinoxalinediones Carrying a Piperazine Residue Represent Highly Potent and Selective Ligands to the Homomeric Kainate Receptor GluR5.

W. Lubisch, B. Behl, C. Henn, H. P. Hofmann, J. Reeb, F. Regner, M. Vierling

Journal:

Year:

2002

File:

PDF, 27 KB

2002

13

Autoradiographic localization of progestin-concentrating cells in the brain of the zebra finch

Jane L. Lubischer, Arthur P. Arnold

Journal:

The Journal of Comparative Neurology

Year:

1990

Language:

english

File:

PDF, 796 KB

english, 1990

14

Umsetzung bifunktioneller Moleküle mit Acceptor-substituierten Butadienen

Wilhelm Flitsch, Wilfried Lubisch, Jürgen Rosche

Journal:

European Journal of Organic Chemistry

Year:

1987

File:

PDF, 536 KB

1987

15

Synthesewege zu 1-substituierten Butadienylphosphonaten

Wilhelm Flitsch, Jürgen Rosche, Wilfried Lubisch

Journal:

European Journal of Organic Chemistry

Year:

1987

Language:

german

File:

PDF, 461 KB

german, 1987

16

Reinnervation of the rat levator ani muscle after neonatal denervation

Jane L. Lubischer, Graciela A. Unguez, David J. Pierotti, Roland R. Roy, V. Reggie Edgerton

Journal:

Developmental Neurobiology

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

17

Transient and permanent effects of androgen during synapse elimination in the levator ani muscle of the rat

Jane L. Lubischer, Cynthia L. Jordan, Arthur P. Arnold

Journal:

Developmental Neurobiology

Year:

1992

Language:

english

File:

PDF, 888 KB

english, 1992

18

Axotomy of developing rat spinal motoneurons: Cell survival, soma size, muscle recovery, and the influence of testosterone

Jane L. Lubischer, Arthur P. Arnold

Journal:

Developmental Neurobiology

Year:

1995

Language:

english

File:

PDF, 1.53 MB

english, 1995

19

Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

Thomas D. Penning, Gui-Dong Zhu, Viraj B. Gandhi, Jianchun Gong, Sheela Thomas, Wilfried Lubisch, Roland Grandel, Wolfgang Wernet, Chang H. Park, Elizabeth H. Fry, Xuesong Liu, Yan Shi, Vered Klinghof

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 384 KB

english, 2008

20

Potent and selective oxindole-based vasopressin 1b receptor antagonists with improved pharmacokinetic properties

Thorsten Oost, Gisela Backfisch, Swati Bhowmik, Marcel M. van Gaalen, Hervé Geneste, Wilfried Hornberger, Wilfried Lubisch, Astrid Netz, Liliane Unger, Wolfgang Wernet

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 473 KB

english, 2011

21

An improved synthesis of [2.2.3]cyclazines from 3H-pyrrolizines

Volker Batroff, Wilhelm Flitsch, Wilfried Lübisch, Derek Leaver, David Skinner

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 203 KB

english, 1982

22

Synthesis and biological evaluation of novel piperidine carboxamide derived calpain inhibitors

W. Lubisch, H.P. Hofmann, H.J. Treiber, A. Möller

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 148 KB

english, 2000

23

Discovery of phenyl alanine derived ketoamides carrying benzoyl residues as novel calpain inhibitors

W. Lubisch, A. Möller

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

24

Pyrrolylquinoxalinediones carrying a piperazine residue represent highly potent and selective ligands to the homomeric kainate receptor GluR5

W Lubisch, B Behl, C Henn, H.P Hofmann, J Reeb, F Regner, M Vierling

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 104 KB

english, 2002

25

Pyrrolylquinoxalinediones: A new class of AMPA receptor antagonists

W. Lubisch, B. Behl, H.P. Hofmann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 295 KB

english, 1996

26

Pyrrolylquinoxalinediones: The importance of pyrrolic substitution on AMPA receptor binding

W. Lubisch, B. Benl, H.P. Hofmann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 266 KB

english, 1997

27

Pyrrolylquinoxalinediones: Dicarboxylates as highly potent AMPA receptor antagonists

W. Lubisch, B. Behl, H.P. Hofmann, H.J. Teschendorf

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 339 KB

english, 1997

28

A new pyrrolyl-quinoxalinedione series of non-NMDA glutamate receptor antagonists: pharmacological characterization and comparison with NBQX and valproate in the kindling model of epilepsy

W. Löscher, H. Lehmann, B. Behl, D. Seemann, H. J. Teschendorf, H. P. Hofmann, W. Lubisch, T. Höger, H. -G. Lemaire, G. Groß

Journal:

European Journal of Neuroscience

Year:

1999

Language:

english

File:

PDF, 726 KB

english, 1999

29

Effect of N-acetylaspartylglutamate (NAAG) on non-quantal and spontaneous quantal release of acetylcholine at the neuromuscular synapse of rat

Artem I. Malomouzh, Eugen E. Nikolsky, Edward M. Lieberman, Jessica A. Sherman, Jane L. Lubischer, Robert M. Grossfeld, Albert Kh. Urazaev

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 339 KB

english, 2005

30

Axotomy transiently down-regulates androgen receptors in motoneurons of the spinal nucleus of the bulbocavernosus

Jane L. Lubischer, Arthur P. Arnold

Journal:

Year:

1995

Language:

english

File:

PDF, 1.16 MB

english, 1995

31

Dexmedetomidine for Procedural Sedation in Children With Autism and Other Behavior Disorders

Nina Lubisch, Rudolph Roskos, John W. Berkenbosch

Journal:

Pediatric Neurology

Year:

2009

Language:

english

File:

PDF, 126 KB

english, 2009

32

Benzoylalanine-Derived Ketoamides Carrying Vinylbenzyl Amino Residues: Discovery of Potent Water-Soluble Calpain Inhibitors with Oral Bioavailability

Lubisch, Wilfried, Beckenbach, Edith, Bopp, Sabina, Hofmann, Hans-Peter, Kartal, Arzu, Kästel, Claudia, Lindner, Tanja, Metz-Garrecht, Marion, Reeb, Jutta, Regner, Ferdinand, Vierling, Michael, Möller

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 131 KB

english, 2003

33

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., Thompson, W. J., Barres, B. A.

Journal:

Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 854 KB

english, 2008

34

Intramuscular Dexmedetomidine: An Effective Route of Sedation Preserves Background Activity for Pediatric Electroencephalograms

Keira P. Mason, Nina Lubisch, Fay Robinson, Rudolph Roskos, Mark A. Epstein

Journal:

The Journal of Pediatrics

Year:

2012

Language:

english

File:

PDF, 381 KB

english, 2012

35

Application of Low-Frequency Alternating Current Electric Fields Via Interdigitated Electrodes: Effects on Cellular Viability, Cytoplasmic Calcium, and Osteogenic Differentiation of Human Adipose-Derived Stem Cells

McCullen, Seth D., McQuilling, John P., Grossfeld, Robert M., Lubischer, Jane L., Clarke, Laura I., Loboa, Elizabeth G.

Journal:

Tissue Engineering Part C Methods

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

36

LES Study of Flow Between Shrouded Co-rotating Disks

Washizu, Tomoya, Lubisch, Florian, Obi, Shinnosuke

Journal:

Flow, Turbulence and Combustion

Year:

2013

Language:

english

File:

PDF, 2.14 MB

english, 2013

37

Intramuscular Dexmedetomidine Sedation for Pediatric MRI and CT

Mason, Keira P., Lubisch, Nina B., Robinson, Fay, Roskos, Rudolph

Journal:

American Journal of Roentgenology

Year:

2011

Language:

english

File:

PDF, 644 KB

english, 2011

38

Kraftstoffsparpotenzial durch Lenkung und Bremse

Dipl.-Ing. Frank Lubischer…

Journal:

ATZ - Automobiltechnische Zeitschrift

Year:

2008

Language:

german

File:

PDF, 1.50 MB

german, 2008

39

The Cell Cycle, Principles of Control. David O. Morgan.

Lubischer, J. L.

Journal:

Integrative and Comparative Biology

Year:

2007

Language:

english

File:

PDF, 49 KB

english, 2007

40

Reduction of myocardial infarction by calpain inhibitors A-705239 and A-705253 in isolated perfused rabbit hearts

Neuhof, Christiane, Fabiunke, Verena, Deibele, Karin, Speth, Maria, Möller, Achim, Lubisch, Wilfried, Fritz, Hans, Tillmanns, Harald, Neuhof, Heinz

Journal:

Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 244 KB

english, 2004

41

A Novel Water-Soluble and Cell-Permeable Calpain Inhibitor Protects Myocardial and Mitochondrial Function in Postischemic Reperfusion

Neuhof, C., Götte, O., Trumbeckaite, S., Attenberger, M., Kuzkaya, N., Gellerich, F., Möller, A., Lubisch, W., Speth, M., Tillmanns, H., Neuhof, H.

Journal:

Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 153 KB

english, 2003

42

Wir brauchen einen Direktstudiengang Psychotherapie – Pro

Lubisch, Barbara

Journal:

Psychiatrische Praxis

Year:

2015

Language:

german

File:

PDF, 104 KB

german, 2015

43

Calpain inhibitor A-558693 in experimental focal cerebral ischemia in rats

Liebetrau, Martin, Martens, Helge, Thomassen, Nora, Burggraf, Dorothe, Gabrijelcic-Geiger, Dusica, Lubisch, Wolfgang, Möller, Achim, Hamann, Gerhard F.

Journal:

Neurological Research

Year:

2005

Language:

english

File:

PDF, 141 KB

english, 2005

44

CALPAIN INHIBITION REDUCES PMN-MEDIATED PULMONARY EDEMA

Neuhof, C., Strunden, M., Maybauer, M., Möller, A., Lubisch, W., Neuhof, H.

Journal:

Year:

2004

File:

PDF, 112 KB

2004

45

Intramuscular dexmedetomidine for pediatric electroencephalogram (EEG) sedation

Mason, K., Lubisch, N., Robinson, F., Roskos, R., Epstein, M.

Journal:

European Journal of Anaesthesiology

Year:

2012

Language:

english

File:

PDF, 257 KB

english, 2012

46

DEXMEDETOMIDINE FOR PEDIATRIC PROCEDURAL SEDATION???RESULTS FROM THE PEDIATRIC SEDATION RESEARCH CONSORTIUM (PSRC)

Berkenbosch, John W., Lubisch, Nina, Gallagher, Susan, Cravero, Joe P.

Journal:

Pediatric Critical Care Medicine

Year:

2006

Language:

english

File:

PDF, 211 KB

english, 2006

47

DEXMEDETOMIDINE FOR PROCEDURAL SEDATION IN CHILDREN WITH PERVASIVE DEVELOPMENTAL DELAY AND NEUROBEHAVIOR DISORDERS

Berkenbosch, John W., Lubisch, Nina, Walls, Kara, Schoonover, Jennifer, Roskos, Rudolph

Journal:

Pediatric Critical Care Medicine

Year:

2006

Language:

english

File:

PDF, 211 KB

english, 2006

48

ChemInform Abstract: Synthetic Routes to 1-Substituted Butadienylphosphonates.

FLITSCH, W., ROSCHE, J., LUBISCH, W.

Journal:

Year:

1987

File:

PDF, 141 KB

1987

49

ChemInform Abstract: Reactions of Bifunctional Molecules with Acceptor-Substituted Butadienes.

FLITSCH, W., LUBISCH, W., ROSCHE, J.

Journal:

Year:

1987

File:

PDF, 197 KB

1987

50

The Cell Cycle, Principles of Controlby David O. Morgan

Review by: Jane L. Lubischer

Journal:

Integrative and Comparative Biology

Year:

2007

Language:

english

File:

PDF, 524 KB

english, 2007